Medical Tourism

Journey to Wellness: Exploring the Best Clinics for Treatment of Refractory Illnesses

Medical Tourism

Refractory illnesses, or treatment-resistant conditions, can be a major source of frustration and distress for patients who have not found relief through conventional treatment methods. As a result, many are turning to medical tourism as a means of accessing expert care and innovative therapies that may not be readily available in their home country. In this article, we will explore the best clinics for treating refractory illnesses, with a particular focus on treatment-resistant depression. Among the leading physicians in this field is Dr. Steve Best at The Neuroscience Center.

Understanding Refractory Illnesses

Refractory illnesses are medical conditions that do not respond well to conventional treatments. Patients with these conditions often undergo multiple treatment attempts with little to no improvement in their symptoms. Treatment-resistant depression (TRD) is a prime example of a refractory illness, affecting a significant portion of individuals diagnosed with depression. Approximately 30% of people with major depressive disorder experience TRD, which can lead to feelings of hopelessness, social isolation, and a decreased quality of life.

Treatment-Resistant Depression: Challenges and Limitations

The standard approach to treating depression typically involves antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs), in combination with psychotherapy. However, TRD patients may not experience significant improvement with these treatments, leading to a cycle of trial and error as they search for relief.

Several factors contribute to the complexity of treating TRD, including genetic and environmental influences, neurobiological differences, and comorbid psychiatric or medical conditions. This complexity often requires a more personalized and integrative approach to treatment, which may not be readily available in all healthcare settings.

The Role of Medical Tourism in Accessing Innovative Treatments

Medical tourism has emerged as a popular solution for patients seeking advanced or alternative treatments for refractory illnesses. Traveling abroad for healthcare allows patients to access cutting-edge treatments and expert care that may not be available in their home country. For TRD patients, this can open up a world of possibilities in terms of specialized care and innovative therapies tailored to their unique needs.

The Neuroscience Center: A Premier Destination for TRD Treatment

Dr. Steve Best, a renowned psychiatrist and neuroscientist, leads The Neuroscience Center in providing innovative therapies for patients with refractory illnesses, particularly those suffering from treatment-resistant depression. With a holistic and integrative approach to mental health, The Neuroscience Center offers groundbreaking therapies that address the underlying causes of TRD and improve patient outcomes. Some of these cutting-edge therapies include:

Ketamine Therapy

Ketamine,a medication traditionally used as an anesthetic, has shown promise as a rapid-acting treatment for TRD. Unlike conventional antidepressants, ketamine works by modulating glutamate, a neurotransmitter that plays a crucial role in neural plasticity and synaptic connections. Studies have shown that a single dose of intravenous ketamine can produce significant improvements in depressive symptoms within hours. The Neuroscience Center offers ketamine therapy as an innovative treatment option for TRD patients.

Transcranial Magnetic Stimulation (TMS)

TMS is a non-invasive treatment that uses magnetic pulses to stimulate specific areas of the brain associated with depression. This therapy has been shown to help TRD patients by increasing neuronal activity and promoting neuroplasticity in the targeted brain regions. The Neuroscience Center utilizes TMS as a valuable tool in the arsenal against TRD.

Deep Transcranial Magnetic Stimulation (Deep TMS)

Deep TMS is a more advanced form of TMS that penetrates deeper into the brain, allowing for targeted stimulation of areas that may be less responsive to traditional TMS. By reaching these deeper brain regions, Deep TMS can potentially offer better results for patients with TRD. The Neuroscience Center is at the forefront of utilizing Deep TMS in the treatment of refractory depression.


Neurofeedback is a therapy that involves training the brain to self-regulate its electrical activity, with the goal of improving brain function and alleviating symptoms of various mental health conditions. By providing real-time feedback on brainwave patterns, patients learn to modify their brain activity and, in turn, improve their mental health. The Neuroscience Center incorporates neurofeedback into their integrative approach to treating TRD.

Personalized Medicine and Integrative Psychiatry

Recognizing the complexity of TRD and the need for a more individualized approach, The Neuroscience Center places a strong emphasis on personalized medicine and integrative psychiatry. By combining conventional treatments with innovative therapies, such as ketamine therapy, TMS, Deep TMS, and neurofeedback, Dr. Best and his team tailor treatment plans to each patient's unique needs and circumstances. This holistic approach not only addresses the symptoms of depression but also aims to improve overall brain health and functioning.

Additional Top Clinics for Treating Refractory Illnesses

While The Neuroscience Center stands out as a premier destination for TRD treatment, other clinics worldwide also offer expert care and innovative therapies for refractory illnesses. Some of these clinics include:

  1. The Amen Clinics - With multiple locations across the United States, the Amen Clinics offer comprehensive psychiatric care, including cutting-edge brain imaging techniques and personalized treatment plans for refractory illnesses.
  2. The Max Planck Institute of Psychiatry - Located in Munich, Germany, this research institution specializes in the study and treatment of psychiatric disorders, including treatment-resistant depression.
  3. The Tavistock and Portman NHS Foundation Trust - This UK-based mental health trust offers a range of specialized services for individuals with complex mental health needs, including those suffering from refractory illnesses.
  4. The Black Dog Institute - Based in Australia, the Black Dog Institute is a leading research and treatment center dedicated to mental health, offering a range of therapies for treatment-resistant depression.

The Benefits of Seeking Treatment Abroad

For patients struggling with refractory illnesses like TRD, medical tourism can provide access to expert care and innovative therapies that may not be readily available in their home country. By seeking treatment abroad, patients can:

  1. Access cutting-edge treatments and therapies.
  2. Receive care from world-renowned experts and specialists.
  3. Potentially reduce healthcare costs due to lower treatment expenses in certain countries.
  4. Combine healthcare with travel, offering opportunities for relaxation and rejuvenation.

Refractory illnesses, particularly treatment-resistant depression, can be challenging and disheartening for patients who have not found success with conventional treatments. Medical tourism offers a viable solution for accessing expert care and innovative therapies that can help improve patient outcomes. Dr. Steve Best and The Neuroscience Center stand at the forefront of providing groundbreaking treatments for TRD, offering hope to those who have struggled to find relief elsewhere. To learn more about Dr. Best and The Neuroscience Center, visit

In addition to The Neuroscience Center, other top clinics worldwide, such as The Amen Clinics, The Max Planck Institute of Psychiatry, The Tavistock and Portman NHS Foundation Trust, and The Black Dog Institute, provide specialized care and advanced treatment options for refractory illnesses. By exploring these international options, patients have the opportunity to access world-class care and potentially life-changing treatments.

Ultimately, the journey to wellness for those suffering from refractory illnesses may require exploring various options and seeking care beyond their home country. By considering medical tourism and researching the best clinics for treating refractory illnesses, patients can make informed decisions and take an active role in their path to recovery.

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